1. Position: Associate Professor of Human Pgysiology
  2. Tel: (0030) 22540-83117
  3. Fax: (0030) 22540-83109
  4. Email: cgiaginis(at)aegean.gr
 
EDUCATION
  • PhD, Medical School, University of Athens (2010)
  • PhD, School of Pharmacy, University of Athens (2008)
  • MSc, School of Pharmacy, University of Athens (2005)
  • BSc, Department of Chemistry, University of Athens (2002)
RESEARCH INTERESTS
  • Evaluation and clinical significance of biological markers, molecular mediators and receptors implicated in pathophysiological states and especially in cancer and atherosclerosis.
  • Nuclear receptors and human metabolism and disease.
  • Physiology and pathophysiology of adipose tissue.
  • Nutrition and cancer.
  • Quantitative Structure-Activity/Property Relationships (QSAR/QSPR): investigation of the biological activity and/or toxicity of drugs, xenobiotics and bioactive food ingredients.
  • Physicochemical properties, absorption and bioavailability of drugs, toxic compounds and bioactive food ingredients.

REPRESENTATIVE PUBLICATIONS

  • Koutsounas I, Theocharis S, Patsouris E, Giaginis C. Pregnane X Receptor (PXR) at the crossroads of human metabolism and disease. Curr Drug Metab 2013;14:341-50.
  • Katsargyris A, Tampaki EC, Giaginis C, Theocharis S. Cranberry as promising natural source of potential anticancer agents: current evidence and future perspectives. Anticancer Agents Med Chem 2012;12:619-30.
  • Giaginis C, Papadopouli A, Zira A, Katsargyris C, Klonaris C, Theocharis S. Clinical implication of osteoprotegerin (OPG) and receptor activator of the nuclear factor κB ligand (RANKL) in patients with advanced carotid atherosclerosis. Med Sci Monit 2012;18(10): CR597-604.
  • Giaginis C, Theocharis S, Tsantili-Kakoulidou A. Current toxicological aspects on drug and chemical transport and metabolism across the human placental barrier. Expert Opin Drug Metab Toxicol 2012;8:1263-75.
  • Giaginis C, Theocharis S. Current evidence on the anticancer potential of Chios mastic gum. Nutr Cancer 2011;63:1174-84.
  • Giaginis C, Klonaris C, Katsargyris A, Spiliopoulou C, Kouraklis G, Theocharis S. Correlation of Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) and Retinoid X Receptor-α (RXR-α) expression with clinical risk factors in patients with advanced carotid atherosclerosis. Med Sci Monit 2011;17:CR381-91.
  • Theocharis S, Klijanienko J, Giaginis C, Rodriguez J, Jouffroy T, Girod A, Point D, Tsourouflis G, Sastre-Garau X. Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) expression in mobile tongue squamous cell carcinoma: associations with clinicopathological parameters and patients survival. J Cancer Res Clin Oncol 2011;137:251-9.
  • Giaginis C, Zira A, Katsargyris A, Klonaris C, Theocharis S. Clinical implication of plasma neutrophil gelatinase-associated lipocalin (NGAL) levels in patients with advanced carotid atherosclerosis. Clin Chem Lab Med 2010;48:1035-41.
  • Giaginis C, Daskalopoulou S, Vgenopoulou S, Sfiniadakis I, Kouraklis G, Theocharis S. Heat Shock Protein (HSP)-27, -60 and -90 expression in gastric cancer: association with clinicopathological variables and patient survival. BMC Gastroenterol 2009;9:14.
  • Giaginis C, Georgiadou M, Dimakopoulou K, Tsourouflis G, Gatzidou E, Kouraklis G, Theocharis S. Clinical significance of MCM-2 and MCM-5 expression in colon cancer: Association with clinicopathological parameters and tumor proliferative capacity. Dig Dis Sci 2009;54:282-91.

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